Aspirin-d3 is the deuterium labeled Aspirin. Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. It induces apoptosis, inhibits the activation of NF-κB, and also inhibits platelet prostaglandin synthetase, which can prevent coronary artery and cerebrovascular thrombosis.
- Deuterium-labeled compound with stable heavy isotopes
- Can affect pharmacokinetic and metabolic profiles of drugs
- Used as a tracer and internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Orally active, potent, and irreversible inhibitor of cyclooxygenase COX-1 and COX-2
- Induces apoptosis, inhibits NF-κB activation, and platelet prostaglandin synthetase